ABSTRACT: The text starts from a research on the history of the minority device in Brazil, that is, the network of knowledge and powers that articulated institutions, professions, discourses, laws and varied educational practices to manufacture the difference between the child and the minor from of the First Republic (1889-1930). For this text, Arthur Ramos’s work “The problem child” (1939) is mobilized in more detail to show and give to read the ways of constituting knowledge about the “disadjusted” child or in a psychic and social situation that would lead him to commit criminal acts such as theft. Based on the theoretical-methodological tools of the genealogy of power and the archeology of knowledge by Michel Foucault, a series of clinical cases recorded in different files from the archives of the Serviço de Ortofrenia e Higiene Mental (SOHM) in Rio de Janeiro is discussed, and the insidious articulations between Education and Psychoanalysis and their ways of constituting knowledge and exercising powers over children's bodies.

RÉSUMÉ: Le texte part d'une recherche sur l'histoire du dispositif minoritaire au Brésil, c'est-à-dire le réseau de savoirs et de pouvoirs qui articule les institutions, les professions, les discours, les lois et les pratiques éducatives variées pour fabriquer la différence entre l'enfant et le mineur à partir de la Première République (1889-1930). Pour ce texte, l'ouvrage d'Arthur Ramos « L'enfant à problèmes » (1939) est mobilisé plus en détail pour montrer et donner à lire les manières de constituer des connaissances sur l'enfant « désajusté » ou dans une situation psychique et sociale qui le conduirait à s'engager. des actes criminels comme le vol. Sur la base des outils théoriques et méthodologiques de la généalogie du pouvoir et de l'archéologie du savoir de Michel Foucault, une série de cas cliniques enregistrés dans différents dossiers des archives du Serviço de Ortofrenia e Higiene Mental (SOHM) à Rio de Janeiro est discutée ., et les articulations insidieuses entre Éducation et Psychanalyse et leurs manières de constituer des savoirs et d'exercer des pouvoirs sur les corps des enfants.

RESUMEN: El texto parte de una investigación sobre la historia del dispositivo minoritario en Brasil, o sea, la red de saberes y poderes que articuló instituciones, profesiones, discursos, leyes y variadas prácticas educativas para fabricar la diferencia entre el niño y el menor de edad. la Primera República (1889-1930). Para este texto se moviliza con más detalle la obra de Arthur Ramos “El niño problema” (1939) para mostrar y dar a leer los modos de constitución del conocimiento sobre el niño “desadaptado” o en una situación psíquica y social que lo llevaría a cometer actos delictivos como el robo. Con base en las herramientas teórico-metodológicas de la genealogía del poder y la arqueología del saber de Michel Foucault, se discute una serie de casos clínicos registrados en diferentes archivos del Serviço de Ortofrenia e Higiene Mental (SOHM) en Río de Janeiro, y las insidiosas articulaciones entre Educación y Psicoanálisis y sus formas de constituir saberes y ejercer poderes sobre los cuerpos de los niños.

RESUMO: O texto parte de uma pesquisa sobre a história do dispositivo da menoridade no Brasil, isto é, a rede de saberes e poderes que articulou instituições, profissões, discursos, leis e práticas educativas variadas para fabricar a diferença entre a criança e o menor a partir da Primeira República (1889-1930). Mobiliza-se mais detidamente para este texto a obra “A criança problema” (1939) de Arthur Ramos para fazer ver e dar a ler os modos de constituição do saber sobre a criança “desajustada” ou em situação psíquica e social que a levaria a praticar atos infracionais como roubo. A partir das ferramentas teórico-metodológicas da genealogia do poder e da arqueologia do saber de Michel Foucault, problematiza-se uma série de casos clínicos registrados em diferentes fichas provenientes dos arquivos do Serviço de Ortofrenia e Higiene Mental (SOHM), no Rio de Janeiro, e as insidiosas articulações entre Educação e Psicanálise e seus modos de constituir saberes e exercer poderes sobre os corpos infantis.

ABSTRACT Objective: To determine the clinical profile of COVID-19 inpatients who were vaccinated prior to hospitalization and to compare the risk factors for death and the 28-day survival rate of between those inpatients vaccinated with one, two, or three doses and unvaccinated COVID-19 inpatients. Methods: This was a retrospective observational cohort study involving COVID-19 patients admitted to a referral hospital in the city of Recife, Brazil, between July of 2020 and June of 2022. Results: The sample comprised 1,921 inpatients, 996 of whom (50.8%) were vaccinated prior to hospitalization. After adjusting the mortality risk for vaccinated patients, those undergoing invasive mechanical ventilation (IMV) had the highest mortality risk (adjusted OR [aOR] = 7.4; 95% CI, 3.8-14.1; p < 0.001), followed by patients > 80 years of age (aOR = 7.3; 95% CI, 3.4-15.4; p < 0.001), and those needing vasopressors (aOR = 5.6; 95% CI, 2.9-10.9; p < 0.001). After adjusting the mortality risk for all patients, having received three vaccine doses (aOR = 0.06; 95% CI, 0.03-0.11; p < 0.001) was the most important protective factor against death. There were progressive benefits of vaccination, reducing the frequency of ICU admissions, use for IMV, and death (respectively, from 44.9%, 39.0% and 39.9% after the first dose to 16.7%, 6.2% and 4.4% after the third dose), as well as significant improvements in survival after each subsequent dose (p < 0.001). Conclusions: Vaccines were effective in reducing illness severity and death in this cohort of COVID-19 inpatients, and the administration of additional doses conferred them with accumulative vaccine protection.

RESUMO Objetivo: Traçar o perfil clínico de pacientes internados com COVID-19 que haviam sido vacinados antes da hospitalização e comparar os fatores de risco para óbito e a taxa de sobrevida em 28 dias entre esses internados vacinados com uma, duas ou três doses e pacientes internados com COVID-19 não vacinados. Métodos: Estudo de coorte observacional retrospectivo envolvendo pacientes com COVID-19 internados em um hospital de referência na cidade do Recife (PE) entre julho de 2020 e junho de 2022. Resultados: A amostra foi composta por 1.921 pacientes internados, dos quais 996 (50,8%) haviam sido vacinados antes da hospitalização. Após ajuste do risco de mortalidade para os pacientes vacinados, aqueles submetidos à ventilação mecânica invasiva (VMI) apresentaram o maior risco de mortalidade (OR ajustada [ORa] = 7,4; IC95%: 3,8-14,1; p < 0,001), seguidos pelos pacientes > 80 anos (ORa = 7,3; IC95%: 3,4-15,4; p < 0,001) e aqueles que necessitam de vasopressores (ORa = 5,6; IC95%: 2,9-10,9; p < 0,001). Após ajuste do risco de mortalidade para todos os pacientes, o recebimento de três doses de vacina (ORa = 0,06; IC95%: 0,03-0,11; p < 0,001) foi o fator de proteção mais importante contra o óbito. Houve benefícios progressivos da vacinação, com redução da frequência de internações em UTI, de uso de VMI e de óbitos (de 44,9%, 39,0% e 39,9% após a primeira dose para 16,7%, 6,2% e 4,4% após a terceira dose, respectivamente), bem como melhora significativa na sobrevida após cada dose subsequente (p < 0,001). Conclusões: As vacinas foram efetivas na redução da gravidade da doença e dos óbitos nesta coorte de pacientes internados com COVID-19, e a aplicação de doses adicionais conferiu-lhes proteção vacinal cumulativa.

Abstract The text analyzes the conditions of historical emergence of the (auto)biographical accounts of Cleonder Evangelista, a young former inmate of the Fundação Estadual do Bem-Estar do Menor in São Paulo (Febem/SP), and Paulo Sergio Farias and Laércio Narciso, two former employees of the institution. It operates with discourse analysis, dividing the approach into three moments: description of the institutional and social scenario marked by crises, denunciations and rebellions between the 1990s and 2000s through the repercussion in the press; problematization of the crossed autobiography of two ex-employees and their criticisms and propositions to the policy of detention of juvenile offenders; analysis of the autobiographical account of a former inmate in its articulation with the report of the employees, mapping the encounter and the interference they had in the construction of a resocialization project through access to higher education under special conditions. From the (auto)biographical narratives, it was possible to map information about FEBEM’s daily life, both in terms of violence and the formation of cooperation networks, something difficult to find in official or press records that, over the years, have documented some stories about Febem/SP, but with different approaches to the story told here.

Resumo O texto analisa as condições de emergência histórica dos relatos (auto)biográficos de Cleonder Evangelista, um jovem ex-interno da Fundação Estadual do Bem-Estar do Menor em São Paulo (Febem/SP), e Paulo Sergio Farias e Laércio Narciso, dois ex-funcionários da instituição. Opera-se com a análise do discurso, dividindo-se a abordagem em três momentos: descrição do cenário institucional e social marcado por crises, denúncias e rebeliões entre os anos 1990 e 2000 por meio da repercussão na imprensa; problematização da autobiografia cruzada de dois ex-funcionários e suas críticas e proposições à política de internação de adolescentes infratores; análise do relato autobiográfico de um ex-interno em sua articulação com o relato dos funcionários, mapeando o encontro e a interferência que tiveram na construção de um projeto de ressocialização por meio do acesso à educação em nível superior em condições especiais. A partir das narrativas (auto)biográficas, foi possível mapear informações sobre o cotidiano da Febem tanto no aspecto da violência, como também sobre a formação de redes de cooperação, algo dificilmente acessável em registros oficiais ou da imprensa, que, ao longo dos anos, documentaram algumas histórias sobre a Febem/SP, mas com enfoques distintos da história que aqui se conta.

RESUMO O objetivo desse trabalho foi avaliar o efeito da aplicação via solo de doses de boro (B), com ou sem adubação com zinco (Zn), sobre o crescimento, componentes de produção e produtividade do Milho em Neossolo Litólico distrófico, com baixos teores de B e Zn. O delineamento experimental utilizado foi blocos casualizados, em esquema fatorial 6 x 2, correspondente a seis doses de (B) aplicadas no solo (0, 1, 2, 3, 4 e 5 kg ha-1) e, sem e com adubação de Zn (2,0 kg ha-1 de Zn), ambas realizadas na semeadura, com quatro repetições. No estádio fenológico R1, foram avaliadas as variáveis de crescimento: diâmetro de colmo e altura de plantas, juntamente com o índice SPAD de clorofila. No estádio fenológico R6 foram analisados comprimento da espiga; massa de mil grãos, produtividade e dose de máxima eficiência (DME). A adubação com boro e zinco aumenta a produtividade do milho em solo com textura franco-argilo arenosa e baixos teores desses elementos, existindo sinergismo na absorção e metabolismo da planta quando se aplica 1,0 kg ha-1 de B juntamente com 2,0 kg de Zn ha-1 via solo no sulco de plantio. Neste estudo, as doses de máxima eficiência técnica para produtividade de grãos foi de 3,29 e 4,31 kg de B ha-1 para os tratamentos sem e com adubação com Zn.

ABSTRACT The objective of this work was to evaluate the effect of soil application of different boron (B) rates to the soil, with and without application of zinc (Zn), on growth, production components, and grain yield of maize crops grown in a Lithic Quartzipsamment with low B and Zn contents. A randomized block experimental design was used, in a 6×2 factorial arrangement corresponding to six B rates (0, 1, 2, 3, 4, and 5 kg ha-1), with and without application of Zn (2.0 kg ha-1), applied to the soil at sowing, with four replications. Growth variables (stem diameter and plant height), and chlorophyll SPAD index were evaluated at the R1 phenological stage. Maize ear length, one-thousand grain weight, and grain yield, and the B maximum efficiency rate were evaluated at the R6 phenological stage. Application of B and Zn to the soil increases maize grain yield in soils with sandy clay loam texture and low B and Zn contents; the plant absorption and metabolism indicated synergism between these elements when using soil applications of 1.0 kg ha-1 of B combined with 2.0 kg ha-1 of Zn to the planting furrows. The rates with maximum technical efficiency for grain yield were 3.29 and 4.31 kg of B ha-1 in treatments without and with application of Zn, respectively.

Abstract Introduction In the last 28 years, the scientific community has been using elastography to evaluate the mechanical properties of biological tissue. The aim of this work was the optimization of the UDmV method, presented in Part I of the series, by means of modifying the technique employed to generate the reference sine and cosine functions, used for phase-quadrature demodulation, and determining how this modification improved the performance of the method. Additionally, the UDmV was employed to characterize the acoustic and mechanical properties of a 7% gelatin phantom. Methods A focused transducer, T F, with a nominal frequency of 2.25 MHz, was used to induce the shear waves, with frequency of 97.644 Hz. Then, the modified UDmV method was used to extract the phase and quadrature components from ultrasonic RF echo-signals collected from four positions along the propagation path of the shear wave, which allowed the investigation of the medium vibration caused by wave propagation. The phase velocity, c s, and attenuation, α s, of the phantom were measured and employed in the calculation of shear modulus, μ, and viscosity, η. Results The computational simulation demonstrated that the modification in UDmV method resulted in more accurate and precise estimates of the initial phases of the reference sinusoidal functions used for phase-quadrature demodulation. The values for c s and μ of 1.31 ± 0.01 m·s-1 and 1.66 ± 0.01 kPa, respectively, are very close to the values found in the literature (1.32 m·s-1 and 1.61 kPa) for the same material. Conclusion The UDmV method allowed estimating of the acoustic and viscoelastic parameters of phantom.

Abstract Introduction Therapeutic ultrasound (TUS) is a widespread modality in physiotherapy, and the water bag technique is a coupling method employed in the presence of anatomical irregularities in the treatment area. The aim of the present study is to evaluate the acoustic attenuation of the water bag and its effectiveness as a TUS coupling agent. Methods The rated output powers (ROPs) of the TUS equipment were evaluated based on IEC 61689. Then, a radiation force balance was used to measure ROP with and without a water bag (latex and nitrile gloves filled with deionized water) between a TUS transducer and the cone-shaped target of the balance. Each experiment was performed five times for each nominal power (0.5, 1.0, 2.0, 3.0, 4.0, 5.0, 6.0, and 7.0 W) and in the following configurations: without the water bag (A), with nitrile gloves and with (B) and without (C) a height controller, and latex gloves with (D) and without (E) height controller. ROPs obtained in different media were compared. Results The highest relative error of ROP was 16.72% for 0.5 W. Although the power values of the equipment were within the range recommended by IEC, there was a significant difference between the ROP values measured with A and with B, C and D. Conclusion As intensity differences below 0.5 W/cm2 are considered clinically not relevant, conditions A, B, C, D, or E can be used interchangeably.

RESUMO Objetivo: descrever o perfil clínico e sociodemográfico de pacientes oncológicos atendidos na emergência de um Centro de Alta Complexidade em Oncologia, observando a cobertura dos cuidados paliativos e assistência domiciliar. Método: estudo de corte transversal com adultos oncológicos atendidos na emergência (setembro a dezembro de 2011) e tempo de permanência superior a 2 horas. Usaram-se teste t-Student de comparação de médias e qui-quadrado. Resultados: participaram 191 pacientes, 47,6% idosos, 64,4% mulheres e 75,4% procedentes de Recife e região metropolitana. Dor (46,6%) foi o sintoma prevalente à admissão. Os pacientes sob cuidados paliativos eram 4,2% e sob atenção domiciliar, 2,1%. Os cânceres mais frequentes foram colo uterino (18,3%), mama (13,6%) e próstata (10,5%), sendo 70,7% em estadios avançados (IV, 47,1%) e 40% sem terapia oncológica. Conclusão: a procura da emergência por causa de dor deveu-se, provavelmente, à baixa cobertura de cuidados paliativos e atenção domiciliar, os quais precisam ser associados precocemente à terapia oncológica para minimização do sofrimento dos pacientes/familiares e integrar as competências de oncologistas e profissionais de emergências.

SUMMARY Objective: To describe the clinical and sociodemographic profile of cancer patients admitted to the Emergency Center for High Complexity Oncologic Assistance, observing the coverage of palliative and home care. Method: Cross sectional study including adult cancer patients admitted to the emergency service (September-December/2011) with a minimum length of hospital stay of two hours. Student’s t-test and Pearson chi-square test were used to compare the means. Results: 191 patients were enrolled, 47.6% elderly, 64.4% women, 75.4% from the city of Recife and greater area. The symptom prevalent at admission was pain (46.6%). 4.2% of patients were linked to palliative care and 2.1% to home care. The most prevalent cancers: cervix (18.3%), breast (13.6%) and prostate (10.5%); 70.7% were in advanced stages (IV, 47.1%); 39.4% without any cancer therapy. Conclusion: Patients sought the emergency service on account of pain, probably due to the incipient coverage of palliative and home care. These actions should be included to oncologic therapy as soon as possible to minimize the suffering of the patient/family and integrate the skills of oncologists and emergency professionals.

Entre os gêneros que exibem nodulação caulinar Aeschynomene e Discolobium são encontrados no Pantanal Mato-grossense (áreas inundáveis no Estado do Mato Grosso, Brasil). Isolados obtidos de nódulos de caule e raiz de D. pulchellum, D. psoraleaefolium, D. leptophyllum and A. fluminensis foram coletados em vários pontos no Pantanal de Poconé e caracterizados fenotípica e genotipicamente, pela análise de restrição do gene 16S rDNA. Dos 282 isolados obtidos de nódulos de caule e raiz 84,3% alcalinizaram o meio YMA e 74,1% apresentaram crescimento lento. Não se observou diferença fenotípica nem genotípica entre as populações de rizóbio isoladas de nódulos radiculares ou caulinares das espécies de Discolobium e de A. fluminensis. Entre os isolados obtidos da espécie Discolobium pulchellum obteve-se um grupo que não agrupou similaridade com nenhuma das estirpes de referência utilizadas e a maior parte dos isolados analisados pelo PCR\RFLP apresentou similaridade com o gênero Bradyrhizobium.

Among the genera that exhibit stem nodulation, Aeschynomene and Discolobium are found in the Pantanal Mato-grossense (wetlands in the state of Mato Grosso, Brazil). Isolates obtained from the stem and root nodules of D. pulchellum, D. psoraleaefolium, D. leptophyllum and A. fluminensis were collected from various locations in the Pantanal de Poconé sub-region and phenotypically characterized and genotyped by restriction analysis of the 16S rDNA gene. Of the 282 isolates obtained from the stem and root nodules, 84.3% alkalized YMA media and 74.1% showed slow growth. No differences in either the phenotype or the genotype among the rhizobial populations isolated from the root or stem nodules of the species Discolobium and A. fluminensis were observed. Among the isolates obtained from D. pulchellum, there was a group that was not similar to any of the reference strains used, and most of the isolates analyzed by PCR-RFLP were similar to the genus Bradyrhizobium.

This report describes the epidemiological and clinical-evolutive characteristics of eight patients with hantavirus pulmonary syndrome (HPS) in Uberaba, Minas Gerais, Brazil. A positive history of contact with rodents was present in 100% of the cases. The time between the onset of symptoms and hospital care was, on average, 3.6 days. All patients showed clinical and laboratory findings suggestive of HPS. Elevated urea and creatinine levels were observed in 6 (75%) cases, PO2 was < 60 mmHg in 100% of the cases, and a chest X-ray demonstrated a bilateral interstitial-alveolar infiltrate. The diagnosis was confirmed by the detection of IgM antibodies against Sin Nombre virus by ELISA. Three patients died as a direct consequence of HPS.